Endocrine Abstracts

Introduction: The anabolic hormones, namely GH, testosterone and dehydroepiandrosterone, as well as the reproductive function of women, enter a period of progressive insufficiency which is characteristically designated as somatopause, andropause and adrenopause respectively. The aim of the study was to compare the endocrine functions between premenopausal and postmenopausal women.Subjects and methods: The study was included 40 premenopausal (mean age 34....

Introduction: Thyroid and parathyroid pathology may coexist; classically, this is described in multiple endocrine neoplasia. Other nonsyndromic scenarios result in pathologies of these endocrine organs coexisting. The aim of the investigation the chracteristics of thyroid pathology in patients with parathyroid adenoma.Subjects and method: The study population included 42 (26 patients age <60 years vs 16 patients age ≥60 years) patients with par...

Introduction: Low serum levels of 25-hydroxyvitamin D (25(OH)D3) lower than has been reported to be prevalent in several autoimmune diseases. The aims of the study were i) to evaluate the 25(OH)D3 levels in patients with Hashimato’s thyroiditis (HT) and ii) to investigate the relationships between 25(OH)D3, TSH, free T4, free T3, and anti-thyroid peroxidase (anti-TPO) levels in elderly patients with HT.Subjects and method: Stud...

Objective: The aim of our study was to investigate the relationships between insulin receptor substrat-1 (IRS-1) and insulin receptor substrat-2 (IRS-2) gene polymorphisms and cardiovascular factors such as blood pressures, BMI, LDL- cholesterol, triglyceride, HOMA-IR, homocysteine, hsCRP and fibrinogen levels in patients with metabolic syndrome (MetS).Subjects and methods: The study population included 100 patients with MetS and 30 patients without MetS...

Introduction: Biochemical and clinical vitamin B12 deficiency has been demonstrated to be highly prevalent among patients with diabetes mellitus. The aims of the study were 1. to compare the vitamin B12 (VB12) levels, and 2. to investigate the relationship between VB12, fasting insulin and HOMA-IR levels in elderly patients with metabolic syndrome (MetS).Subjects and method: Study population included 121 (mean age 64.3±14.1 years) (80 female, 41 mal...

The aims of the study were to determine the frequency of falls in elderly patients with type 2 diabetes mellitus and to evaluate the risk factors for falls. In the study, 100 (mean age 64.9±11.0 years) (65 females, 35 males) elderly patients with type 2 DM were enrolled. Medical record abstraction of sociodemographic, clinical, and laboratory data was performed retrospectively. Medication characteristics, comorbidities, location and height of fall, associated injuries and...

Objective: In recent years, many studies have been conducted on the beneficial effects of vitamin D. Vitamin D have many important effects on calcium metabolism, skeletal system and also on different systems. Low serum vitamin D levels are predictors of type 2 diabetes mellitus, cancer, cardiovascular diseases, immunological diseases and even mortality. The relationships between vitamin D and cardiovascular diseases can be explained by the lipid-lowering effect of vitamin D. I...